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α-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers | Nature Chemical Biology

Clinical features include abnormal peripheral blood leukocyte counts, anemia, thrombocytopenia, and extensive infiltration of the bone marrow by immature myeloid cells (3, 8)

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The body can convert hydroxy-B12 to use for energy, into other forms of B12 that the body might need, or to help process the synthetic variant